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Indications and Contraindications

Treatment Goals: Alleviation of pain and vertebral body stabilization

 

Indications

Painful Fractures

  • Osteoporotic fracture refractory to medical therapy
  • Benign or malignant tumor: hemangioma, multiple myeloma, metastatic lesion
  • Osteonecrosis

Unstable Fractures

  • Unstable fractures with movement at wedge deformity
  • Multiple thoracic compression deformities with decreased thoracic cage threatens pulmonary compromise, impacts appetite, GI function, balance
  • Possible structural reinforcement prior to surgical stabilization

 

Patient Selection

  • Focused pain in region of fracture
  • Fracture tender to palpation
  • Absence of radicular pain
  • Subacute or acute fractures less than one year old yield greatest results (less than 4-6 months ideal); older fractures can also be treated
  • Fracture unresponsive to medical therapy (analgesics, bedrest, immobilization)
  • Fracture with activity on bone scan or edema on MRI, if in combination with other selection criteria
  • Pain from fracture negatively impacting mobility and ADLs

 

Contraindications

Absolute Contraindications

  • Asymptomatic stable fracture
  • Clinically effective medical therapy
  • Osteomyelitis of target vertebra
  • Uncorrected coagulation disorders
  • Acute traumatic fracture of non-osteoporotic vertebra
  • Prophylaxis with no evidence of acute fracture
  • Allergy to any required component
  • Local or systemic infection

Relative Contraindications

  • Radicular pain or radiculopathy caused by a compressive syndrome unrelated to vertebral body collapse
  • Retropulsed fragment with > 20% spinal canal compromise
  • Tumor extension into epidural space
  • Severe vertebral body collapse (vertebra plana)
  • Stable fracture without pain older than one year

Review additional information about compression fracture treatment.

 

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